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. Author manuscript; available in PMC: 2018 Feb 21.
Published in final edited form as: Biochemistry. 2017 Feb 8;56(7):977–985. doi: 10.1021/acs.biochem.6b01252

Table 4.

Relative Free Energies (ΔG) of the Early Dimer Dissociation Intermediates

(kJ/mol) WT H4K16ac H3K56ac
High FRET5.5 −4.8 ± 0.8 −3.0 ± 0.5 −2.6 ± 0.8
Mid FRET5.5 −1.5 ± 0.9 −2.1 ± 0.6 −1.2 ± 0.9
Low1 FRET5.5   0.28 ± 0.87 −1.1 ± 0.5   0.24 ± 0.86
Low0 FRET5.5 0 0 0