Renal net acid excretion (a), urinary calcium excretion (b), urinary magnesium excretion (c), and urinary sulfate excretion (d), based on 24-hr urine collections in participants with PKU who consumed AA-MF or GMP-MF, n = 8. Values are means ± SE. The dashed lines (b, c, d) represent the reference range for urinary calcium excretion (100–300 mg/d), magnesium excretion (12–293 mg/d), and urinary sulfate excretion (0–30 mEq/d). Results indicate significant increases in renal net acid excretion (p = 0.002), urinary calcium (p = 0.012), magnesium (p = 0.029), and sulfate (p = 0.0008) excretion with AA-MF compared to GMP-MF. AA-MF, amino acid medical foods; GMP-MF, glycomacropeptide medical foods.