Fig. 7.

Response time of redox switches to H₂O₂. Plots of Eq. 5A show the time needed to reach 50% of the overall response of sensors to H₂O₂. Values of rate constants are the same as those used in Fig. 6. In (A) k_switchoff value was 2×10⁻³ s⁻¹, while in (B) the influence of a range of k_switchoff values is shown for peroxiredoxin 5. Input H₂O₂ concentrations supporting rapid information transmission by redox switches are shown in green and were defined as the input eliciting responses faster than 10 min. Nonetheless, some processes may be compatible with longer responses times to H₂O₂, including for example apoptosis [45] or adaptation pathways [46], [47].