Table 1. Mutation spectra.

	% of mutations				P value of effect on % of mutations
	Human germline	Mouse germline	Human somatic	Mouse somatic	Human versus mouse	Germline versus somatic	Interaction
CG->AT	9.78	7.89	19.68	7.10	0.0005	0.001	0.005
CG->GC	5.97	7.30	9.52	4.84	0.27	0.21	0.01
CG->TA	41.21	38.21	25.97	19.30	0.25	9.07E-07	0.54
TA->AT	9.68	8.79	8.03	13.02	0.89	0.29	0.005
TA->CG	27.50	31.43	28.40	30.62	0.06	0.78	0.42
TA->GC	5.87	6.38	8.41	25.12	8.4E-07	3.9E-9	7.3E-08

Germline and somatic mutation spectra in humans and mice.

P values calculated by ANOVA: df=1 for all comparisons; F=15.003, 12.665, 9.161, 1.248, 1.640, 7.336, 1.392, 37.292, 0.391, 0.016, 1.112, 9.406, 3.960, 0.077, 0.664, 37.60, 65.42 and 49.07.