Figure 1.
Effects of CP 55 940 (circles) and Δ9-tetrahydrocannabinol (THC) (triangles) on food-maintained responding (filled symbols) and body temperature (open symbols) in individual rhesus monkeys (n=9). CP 55 940 and THC were administered non-contingently 1 min prior to the start of the session and body temperature was recorded prior to each injection and then again 60 min following the start of the session. Tolerance to the rate-decreasing effects of THC on food-maintained responding was developed by repeated administration across consecutive sessions (filled squares). Abscissae: Dose of CP 55 940 and THC in μg/kg. Left ordinate: Mean (±SD) response rate expressed as a percentage of baseline. Right ordinate: Mean (±SD) change in body temperature expressed in °C.