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. 2017 May 3;15(6):3963–3968. doi: 10.3892/mmr.2017.6545

Figure 4.

Figure 4.

Activation of caspase-3 and caspase-9. (A) Western blot analysis of casp-3, casp-9 and β-actin protein expression in RhoA siRNA-transfected SPCA1 cells and untreated controls using anti-casp-3, anti-casp-9 and β-actin antibodies. β-actin was used as a loading control. (B) A significant increase in the active casp-3 form was observed in RhoA siRNA-transfected cells when compared with the control cells. By contrast, RhoA knockdown did not significantly alter casp-9 activation. **P<0.01 vs. control. RhoA, Ras homolog family member A; siRNA, small interfering RNA; casp-3, caspase-3; casp-9, caspase-9.