Table 1.
Summary of B-scan SD-OCT reflectivity patterns of the presented dots, spots and other white retinal lesions
| Condition | SD-OCT reflectivity pattern | Associated figure |
|---|---|---|
| Inner retinal lesions | ||
| MRNF | Hyper-reflective thickened RNFL | Figure 2 |
| Cotton wool spots (CWS) | Nodule-shaped hyper-reflective thickened area within the RNFL | Figure 3 |
| Outer retinal lesions | ||
| Hard exudates | Hyper-reflective minute dots at the level of OPL | Figure 4 |
| Edema residues | Hyper-reflective deposits within the photoreceptor outer segment layer | Figure 8 |
| RPE lesions/sub-RPE deposits | ||
| Cuticular hard drusen | Discrete dome-shaped sub-RPE deposits; RPE is elevated; PIL is thinner, but present and intact | Figure 9 |
| Infiltrative hard drusen | Discrete sub-RPE deposits that infiltrate through the RPE and PIL; disrupted RPE and PIL | Figure 10 |
| Subretinal drusenoid deposits | Punctuate deposits localized between the RPE and the PIL layers; RPE is not elevated; intact RPE and PIL | Figure 11 |
| Soft drusen | Sub-RPE deposits; RPE is largely elevated; compromised PIL above the deposits; visualization of Bruch’s membrane | Figure 12 |
| Geographical atrophy | Localized absence of PIL and RPE layers; visualization of Bruch’s membrane | Figure 13 |
| Fundus albi | Hyper-reflective deposits located anterior to RPE; straddling through the PIL; intact RPE and PIL | Figure 14 |
| RPE lesions/RPE migration and RPE atrophy | ||
| Fundus flavimaculatus | RPE migration, leaving areas of RPE dropout | Figure 16 |
| Bietti crystalline dystrophy | Hyper-reflective dots on top of Bruch’s membrane; complete absence of PIL; attenuated RPE; visualization of Bruch’s membrane | Figure 18 |
| PIC | Complete loss of all retinal layers, including Bruch’s membrane, at the level of white lesions | Figure 19 |
| POHS | Pigment deposition; RPE migration and atrophy | Figure 20 |
| Post-PRP chorioretinal scar | RPE atrophy, absence of PIL, visualization of Bruch’s membrane | Figure 21 |
| Osseous choristoma | Thickened inner retina, intact RPE and PIL, no mass observed | Figure 22 |
Abbreviations: MRNF, myelinated retinal nerve fiber layer; RNFL, retinal nerve fiber layer; OPL, outer plexiform layer; CWS, cotton wool spots; RPE, retinal pigment epithelium; PIL, photoreceptor integrity line; PIC, punctate inner choroidopathy; POHS, presumed ocular histoplasmosis syndrome; PRP, pan-retinal photocoagulation.