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APS partially restored H2O2-induced decrease of cGMP levels in human umbilical vein endothelial cells. Cells were pretreated 0, 0.1, 1 or 10 µg/ml APS for 1 h prior to incubation with 400 µM H2O2. Data are expressed as the mean ± standard deviation. ##P<0.01 vs. control; **P<0.01 vs. H2O2 only. APS, Astragalus polysaccharide; cGMP, cyclic guanosine monophosphate.
