Figure 1.

Differentially expressed miRs in medulloblastoma tissue compared with normal control tissue, visualized through clustering of sample data using the gplots package in R software. Red represents a miR expression level above the mean; green represents a miR expression level below the mean. The differentially expressed miRs were validated with the data in Gene Expression Omnibus database and the PubMed database articles. miRs miR-17-5p, miR-148a, miR-18a, miR-19a and miR-106a were co-upregulated in medulloblastoma. miR-383, miR-328, miR-128a/b, miR-133b, miR-149, miR-181b, miR-138 and miR-154 were co-downregulated in medulloblastoma. miR, microRNA.