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. 2017 Mar 12;8(6):913–923. doi: 10.7150/jca.17301

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A shows comparative cytotoxicity of ABZ in SBE- β-CD with that of ABZ in ethanol whilst B shows a similar comparative cytotoxicity in normal HOSE cells. C and D show the variation of abdominal circumference and body weight during the treatment period (14 - 36 days). The weight and abdominal circumference was stable to 32 days. E shows the ascites volume measured at day 36 (at euthanasia) in the control versus treated groups for the ABZ-SBE-β-CD as opposed to ABZ suspension in HPMC. ABZ- SBE- β-CD treated groups shows substantial ascities volume control (p = 0.0135). Similar comparison of weight of the tumours recovered at day 36. F shows that neither ABZ- SBE- β-CD nor ABZ in HPMC had any significant effect. HOSE= Human ovarian surface epithelial; SBE-β-CD = sulfobutylether-β- cyclodextrin; HP-β-CD = Hydroxypropyl -β-cyclodextrin; HPMC= Hydroxypropylmethylcellulose.