Table 3.
Maximum quantity of ionised ABZ addition to different percentages of CDs for best complexation and solubilisation of ABZ.
| SBE-β-CD | HP-β-CD | |||
|---|---|---|---|---|
| CD % | Z (mg/ml) | L (µg/ml) | Z (mg/ml) | L (µg/ml) |
| 10 | 3 | 1869±86 | 3 | 1010±61 |
| 20 | 5 | 3800±112 | 4 | 2342±82 |
| 30 | 7 | 5889±120 | 6 | 4600±101 |
| 40 | 8 | 7940±140 | 7 | 6460±110 |
Table 3 shows the maximum amount of ionised ABZ that can be added before inhibition of complexation occurs. Z = maximum concentration (mg/ml) of ABZ that can be added after which inhibition of complexation occurs; L = maximum amount (µg/ml of ABZ) that was complexed to the CD at 25ºC; SBE-β-CD = sulfobutylether-β- cyclodextrin; HP-β-CD = Hydroxypropyl -β-cyclodextrin.