Table 2.
MLN-. LNR-, and LODDS-based prognostic models.
| Variable | MLN-based model | LNR-based model | LODDS-based model | |||||
|---|---|---|---|---|---|---|---|---|
| Hazard ratio | P value | Hazard ratio | P value | Hazard ratio | P value | |||
| MLNa | 1.333 (1.309-1.356) | < 0.001 | ||||||
| LNRb | 6.528 (6.017-7.082) | < 0.001 | ||||||
| LODDS | 1.325 (1.300-1.330) | < 0.001 | ||||||
| NLNc | 0.734 (0.719-0.749) | < 0.001 | ||||||
| Race | < 0.001 | < 0.001 | < 0.001 | |||||
| White | 1 | 1 | 1 | |||||
| Black | 1.151 (1.083-1.224) | 1.143 (1.075-1.215) | 1.151 (1.085-1.225) | |||||
| Other | 0.874 (0.831-0.919) | 0.859 (0.817-0.903) | 0.877 (0.834-0.922) | |||||
| Age | 1.020 (1.018-1.022) | < 0.001 | 1.020 (1.018-1.022) | < 0.001 | ||||
| Aged | 4.776 (4.239-5.380) | < 0.001 | ||||||
| Gender | < 0.001 | |||||||
| Female | 1 | 1 | 1 | |||||
| Male | 1.083 (1.039-1.128) | 1.09 (1.048-1.137) | 1.082 (1.039-1.128) | |||||
| Tumour Location | < 0.001 | < 0.001 | < 0.001 | |||||
| Cardia | 1 | 1 | 1 | |||||
| Upper one-third | 0.898 (0.817-0.987) | 0.902 (0.821-0.992) | 0.893 (0.813-0.982) | |||||
| Middle one-third | 0.787 (0.735-0.842) | 0.787 (0.736-0.843) | 0.783 (0.732-0837) | |||||
| Lower one-third | 0.838 (0.798-0.879) | 0.845 (0.805-0.887) | 0.836 (0.797-0.877) | |||||
| Tumour sizee | 1.128 (1.087-1.171) | < 0.001 | 1.118 (1.078-1.159) | < 0.001 | 1.131 (1.091-1.174) | < 0.001 | ||
| Tumour differentiation | < 0.001 | < 0.001 | < 0.001 | |||||
| Poorly or undifferentiated | 1 | 1 | 1 | |||||
| Well or moderately differentiated | 0.898 (0.861-0.937) | 0.900 (0.863-0.939) | 0.897 (0.860-0.935) | |||||
| T stage | < 0.001 | < 0.001 | < 0.001 | |||||
| T1 | 1 | 1 | 1 | |||||
| T2 | 1.403 (1.300-1.515) | 1.367 (1.266-1.476) | 1.407 (1.303-1.519) | |||||
| T3 | 1.835 (1.710-1.968) | 1.773 (1.654-1.901) | 1.849 (1.725-1.981) | |||||
| T4a | 2.249 (2.093-2.416) | 2.220 (2.068-2.384) | 2.268 (2.113-2.435) | |||||
| T4b | 3.174 (2.916-3.454) | 3.148 (2.893-3.427) | 3.194 (2.936-3.475) | |||||
MLN, metastatic lymph node; NLN, negative lymph node; LNR, lymph node ratio; LODDS, log ratio of metastatic lymph node.
a. In the MLN-based model, MLN had a non-linear effect on the log hazard of survival. Therefore, loge (MLN+0.5) was included in the model to fit a linear form.
b. In the LNR-based model, LNR had a non-linear effect on the log hazard of survival. Therefore, was included in the model to fit a linear form.
In the MLN-based model, NLN had a non-linear effect on the log hazard of survival. Therefore, loge [(NLN+1)/10] was included in the model to fit a linear form.
c. In the LNR-based model, age had a non-linear effect on the log hazard of survival. Therefore, (Age/100)2 was included in the model to fit a linear form.
d. In the MLN-, LNR-, and LODDS-based models, tumour size had a non-linear effect on the log hazard of survival. Therefore, loge (size/10) was included in the models to fit a linear form.