Table 3.
Univariate and multivariate analysis of prognostic factors for PFS.
| Univariate analysis | Multivariate analysis | ||
|---|---|---|---|
| Variables | P value | HR (95%CI) | P value |
| Age (>60 vs. <=60) |
0.004 | 2.031 (1.288-3.203) | 0.002 |
| Gender (male vs. female) |
0.586 | 1.158 (0.786-1.707) | 0.459 |
| B symptoms (yes vs. no) |
0.803 | 1.303 (0.882-1.925) | 0.183 |
| Ann Arbor stage (II vs. I) |
0.032 | 1.354 (0.908-2.018) | 0.137 |
| LDH (elevated vs. normal) |
0.030 | 1.246 (0.792-1.961) | 0.341 |
| local tumor invasiveness (yes vs. no) |
0.028 | 1.298 (0.861-1.956) | 0.212 |
| Treatment (chemotherapy vs. radiotherapy or both) |
0.000 | 2.746 (1.842-4.091) | 0.000 |
| Regimens of chemotherapy (asparaginase-based vs. others) |
0.000 | 2.367 (1.468-3.818) | 0.000 |
| Absolute lymphocyte count (≤1.5×109/L vs. >1.5×109/L) |
0.035 | 1.005 (0.667-1.514) | 0.981 |
| Absolute monocyte count (≤0.5×109/L vs. >0.5×109/L) |
0.152 | 1.045 (0.689-1.585) | 0.837 |
| LMR (≤2.0 vs.>2.0) |
0.000 | 1.763 (1.119-2.777) | 0.014 |