Table 4.
Univariate and multivariate analysis of prognostic factors for OS.
| Univariate analysis | Multivariate analysis | ||
|---|---|---|---|
| Variables | P value | HR (95%CI) | P value |
| Age (>60 vs. <=60) |
0.001 | 2.711 (1.536-4.787) | 0.001 |
| Gender (male vs. female) |
0.173 | 1.494 (0.881-2.534) | 0.137 |
| B symptoms (yes vs. no) |
0.760 | 1.320 (0.810-2.151) | 0.265 |
| Ann Arbor stage (II vs. I) |
0.005 | 1.348 (0.818-2.222) | 0.241 |
| LDH (elevated vs. normal) |
0.001 | 1.725 (0.998-2.982) | 0.051 |
| local tumor invasiveness (yes vs. no) |
0.001 | 2.252 (1.246-4.071) | 0.007 |
| Treatment (chemotherapy vs. radiotherapy or both) |
0.000 | 2.172 (1.287-3.667) | 0.004 |
| Regimens of chemotherapy (asparaginase-based vs. others) |
0.000 | 3.952 (1.984-7.871) | 0.000 |
| Absolute lymphocyte count (≤1.5×109/L vs. >1.5×109/L) |
0.010 | 0.963 (0.567-1.637) | 0.890 |
| Absolute monocyte count (≤0.5×109/L vs. >0.5×109/L) |
0.925 | 1.631 (0.950-2.801) | 0.076 |
| LMR (≤2.0 vs.>2.0) |
0.000 | 2.230 (1.237-4.018) | 0.008 |