Table 4.
Multivariate analysis
| Parameter | DSS | LRFS | MeFS | ||||||
|---|---|---|---|---|---|---|---|---|---|
| H.R. | 95% CI | P Value | H.R. | 95% CI | P Value | H.R. | 95% CI | P Value | |
| Tumor regression grade | 2.100 | 1.063-4.167 | 0.033* | 2.941 | 1.335-6.494 | 0.007* | 2.415 | 1.214-4.808 | 0.012* |
| EphA4 expression | 2.528 | 1.131-5.651 | 0.024* | - | - | - | 3.908 | 1.590-9.601 | 0.003* |
| Vascular invasion | 2.017 | 0.795-5.120 | 0.140 | 3.034 | 1.093-8.420 | 0.033* | - | - | - |
| Post-Tx tumor status | 2.514 | 1.051-6.051 | 0.038* | 2.141 | 0.863-5.311 | 0.101 | 1.910 | 0.831-4.387 | 0.127 |
| Pre-Tx nodal status | - | - | - | 1.849 | 0.969-3.527 | 0.062 | - | - | - |
H.R., hazard ratio; CI, confidence interval; DSS, disease-specific survival; LRFS, local recurrence-free survival; MeFS, metastasis-free survival; *, statistically significant.