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. 2017 Apr 27;15(6):4132–4138. doi: 10.3892/mmr.2017.6517

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Copyright: © Kim et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Effects of PPI on antioxidant enzymes mRNA expressions in H₂O₂ treated HepG2 cells. (A) Reverse transcription-polymerase chain reaction analysis of SOD, GPx, CAT and TRR. (B-E) Data quantification of antioxidant enzyme/GAPDH mRNA expression for (B) CAT, (C) GPx, (D) SOD, and (E) TRR. Values represent the mean ± standard deviation (n=3). *P<0.05 vs. untreated control; ^#P<0.05 vs. H₂O₂-treated control. -, control cells without H₂O₂; +, control cells treated with 1 mM H₂O₂; CAT, catalase; GPx, glutathione peroxidase; H₂O₂, hydrogen peroxide; PPI, peptidylprolyl cis-trans isomerase; ROS, reactive oxygen species; SOD, superoxide dismutase; TRR, thioredoxin reductase.