. Author manuscript; available in PMC: 2017 Dec 1.

Published in final edited form as: Curr Treat Options Infect Dis. 2016 Oct 11;8(4):275–296. doi: 10.1007/s40506-016-0086-4

Table 7.

Treatment of Mycobacterium simiae

Regimen	Drug	Dose and schedule	Known adverse effects

No proven regimen. Relationship of in vitro susceptibility and clinical outcome is not clear.	Clarithromycin and	1000 mg QD	See above
	Rifampin and	10 mg/kg QD (max 600 mg)	See above
	Ethambutol	15 mg/kg QD (max 2.4 grams)	See above
	± Moxifloxacin	400 mg QD	See above
	± Trimethoprim-sulfamethoxazole	One double-strength tablet BID	Hypersensitivity, rash, myelosuppression, interstitial nephritis, increased liver function tests

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