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. 2017 Apr 1;2(1):72–80. doi: 10.1089/can.2016.0035

Table 1.

Biological Actions of Natural and Synthetic Cannabinoid Ligands on Endometriosis

Cannabinoid ligands Actions Effect on endometriosis References
WIN 55212-2 Agonist CB1/CB2 Decreased cell proliferation in vivo and in vitro Leconte et al.8
AM251 Antagonist/inverse agonist CB1 Increased endometriosis-associated hyperalgesia Dmitrieva et al.11
Methanandamide Agonist CB1 Induced endometrial stromal cell migration Gentilini et al.12
D9-THC Agonist CB1/CB2 Induced migration of HEC-1B (human endometrial cell line) McHugh et al.55