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. 2017 Apr;12(4):509–517. doi: 10.4103/1673-5374.204999

Figure 3.

Figure 3

Adult neural stem cells (NSCs) reside within the ependymal cell layer lining the spinal cord central canal.

(A) The central canal of the intact spinal cord harbors ependymal cells/NSCs that can self-renew but are otherwise quiescent. (B) Upon injury of the spinal cord (indicated by the yellow area and accumulation of astrocytes forming a glial scar) these quiescent spinal cord NSCs become activated, proliferate and migrate towards the lesion to differentiate and replace cells of the neuronal and glial lineages.