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Schematic view of the approach proposed.
(A) The injection of acellular extracellular matrix (ECM) form embryo central nervous system (CNS) in the injured spinal cord results in partial regeneration. (B) Laminin, osteopontin and SCO-spondin are expressed together during axonal commissure formation, and all of them have properties in axonal growth, neurodifferentiation and CNS injury. Their combination in CNS injury therapies is a promissory approach.
