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. 2017 May 17;15:104. doi: 10.1186/s12916-017-0865-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Tornado analysis of expected QALYs per worker over 20 years: 3% discount rate. TB tuberculosis, HCWs healthcare workers, LTBI latent tuberculosis infection, QALYs quality-adjusted life years. The most influential input variables were risk of TB exposure (especially for intermediate-risk HCWs), risk of progression to active TB following new infection and risk of infection after exposure, risk of death with active TB, QALY decrements attributed to latent TB treatment and active TB, and proportion of workers performing high-risk duties