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. 2017 May 17;12:11. doi: 10.1186/s13062-017-0182-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The bilaterally symmetrical body plan of most animals is generated by two, perpendicularly acting diffusible morphogen gradients: Wnt and BMP. The figure has been inspired by Fig. five of [5]. Note that the BMP gradient is oriented in the opposite direction in chordates