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shRNA activity of CXCL8 (A), CXCR1 (B) and CXCR2 (C) in a panel of cancer cell lines. Data obtained from Project Achilles Data Portal of Broad Institute (https://www.broadinstitute.org/achilles ). shRNA score denotes log2 based decrease in CXCL8, CXCR1 or CXCR2 shRNA compared to pooled shRNA in cancer cell lines after several rounds of proliferation post-shRNA infection. A negative shRNA score indicates decreased cancer cell proliferation post-shRNA transfection.
