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. 2017 May 18;12(5):e0176665. doi: 10.1371/journal.pone.0176665

Table 6. Variables related to the risk of persistent or non-persistent metabolic syndrome.

Multivariate analysis.

Type of episode 1 persistent episode 1 non-persistent episode >1 non-persistent episode
HR 95% CI HR 95% CI HR 95% CI HR 95% CI
Gender [men] Women 0.99 0.96–1.02 0.87 0.81–0.95 0.87 0.81–0.95
Age [<25 years], 25–29 1.01 0.71–1.44 1.38 1.03–1.86 1.38 1.03–1.86
    30–34 1.03 0.64–1.39 2.06 1.58–2.70 2.06 1.58–2.70
    35–39 1.04 0.79–1.25 2.60 2.01–3.37 2.60 2.01–3.36
    40–44 1.08 0.99–1.17 3.10 2.41–3.98 3.09 2.40–3.90
    45–49 1.15 1.06–1.24 3.57 2.79–4.57 3.56 2.78–4.56
    50–54 1.28 1.19–1.39 4.49 3.51–5.74 4.47 3.50–5.72
    55–59 1.40 1.30–1.52 4.81 3.77–6.16 4.80 3.76–6.13
    60–64 1.51 1.39–1.63 5.46 4.27–6.95 5.44 4.26–6.96
    65–69 1.50 1.39–1.63 5.72 4.47–7.33 5.70 4.45–7.30
    70–74 1.63 1.50–1.76 5.16 4.02–6.62 5.13 4.00–6.59
    75–79 1.82 1.68–1.98 5.31 4.12–6.85 5.29 4.10–6.80
    80–84 2.11 1.93–3.31 6.00 4.61–7.82 5.97 4.59–7.77
    ≥85 2.45 2.21–2.73 7.05 5.29–9.40 7.00 5.26–9.35
Triglycerides≥150 mg/dL 1.14 1.09–1.19 0.98 0.92–1.04 0.98 0.92–1.04
Obesity (BMI≥30 Kg/m2) 0.72 0.60–0.72 0.97 0.93–1.01 0.97 0.93–1.01
Low HDL-cholesterol 1.32 1.27–1.38 0.94 0.87–1.01 0.94 0.87–1.01
DM2 0.81 0.78–0.84 2.20 2.09–2.35 2.22 2.10–2.35
Impaired fasting glucose 1.25 1.16–1.35 1.33 1.19–1.49 1.33 1.19–1.49
Hypertension 0.80 0.76–0.83 2.14 2.01–2.27 2.15 2.02–2.28
High-normal BP 2.92 2.81–3.03 1.57 1.45–1.70 1.57 1.45–1.70
Smoking [never] Yes 1.37 1.31–1.43 1.39 1.27–1.53 1.39 1.26–1.52
    Ex-smoker 0.73 0.67–0.80 1.07 0.92–1.25 1.07 0.92–1.25
Alcohol [no] Yes 1.21 1.08–1.36 1.40 1.14–1.72 1.40 1.14–1.72
    Ex-consumer 0.76 0.62–0.92 0.94 0.68–1.29 0.94 0.68–1.29

Reference category in square brackets.

CI: credibility interval; High-normal BP blood pressure: blood pressure between 130-139/and/or 85–89 mmHg; Impaired fasting glucose: ≥ 110 mg/dL; HDL: high density lipoprotein; DM2: type 2 diabetes mellitus.

Adjusted for: country of origin (Spain, other), number of chronic diseases, antihypertensive drugs, antidiabetic drugs, hypolipemiant drugs and non-steroidal anti-inflammatory drugs.