Table 3. Distribution of SNPs genotyping in case (patients with esophageal, lung or gastric cancer) and controls (normal healthy subjects).
SNPs | Gene | Allele | MAF(n) | P | OR | 95%CI | Reference number | Cancer type | ||
---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | |||||||||
rs36600 | MTMR3 | T/C | 0.117(1978) | 0.086(2540) | 0.0000 | 1.38 | 1.21 | 1.58 | [14] | LC |
Rs3769823 | CASP8 | T/C | 0.29(2961) | 0.27(3400) | 0.0001 | 1.29 | 1.18 | 1.38 | [9] | EC |
Rs2244438 | TRAK2 | G/A | 0.25(2961) | 0.23(3400) | 0.000 | 1.35 | 1.26 | 1.49 | [9] | EC |
rs748404 | TGM5 | C/T | 0.825(1447) | 0.797(36256) | 0.0005 | 1.08 | 1.33 | 1.20 | [16] | LC |
rs9841504 | ZBTB20 | G/C | 0.09(4294) | 0.14(5882) | 0.000 | 0.58 | 0.47 | 0.72 | [20] | GA |
rs2909430 | TP53 | G/A | 0.17(443) | 0.10(547) | 0.000 | 1.94 | 1.06 | 3.57 | [18] | LC |
rs78378222 | TP53 | A/C | 0.21(1014) | 0.19(1839) | 0.0001 | 0.85 | 0.46 | 1.53 | [19] | LC |
rs10931936 | CASP8 | T/C | 0.27(1974) | 0.31(2617) | 0.0000 | 1.29 | 1.19 | 1.40 | [3] | EC |
rs4254535 | GKN2/GKN1 | C/T | 0.67(1452) | 0.68(36203) | 0.0000 | 0.97 | 0.89 | 1.05 | [16] | LC |
rs13042395 | C20orf54 | T/C | 0.47(380) | 0.48(380) | 0.0000 | 0.98 | 0.72 | 1.33 | [20] | EC |
rs8034191 | AGPHD1 | C/T | 0.21(467) | 0.16(388) | 0.0036 | 1.61 | 1.17 | 2.21 | [15,17] | LC |
rs7578456 | TRAK2 | A/G | 0.24(1974) | 0.28(2617) | 0.0000 | 1.27 | 0.17 | 1.38 | [11] | EC |
rs2352028 | GPC5 | T/C | 0.32(295) | 0.35(598) | 0.0000 | 0.89 | 0.66 | 1.20 | [13] | LC |
rs13016963 | ALS2CR12 | A/G | 0.27(2961) | 0.31(3400) | 0.0000 | 1.29 | 1.19 | 1.40 | [9] | EC |
rs4975616 | TERT/CLPTM1 | G/A | 0.42(239) | 0.48(553) | 0.001 | 0.56 | 0.40 | 0.80 | [16] | LC |
rs1530057 | RBMS3 | A/C | 0.05(1429) | 0.05(36224) | 0.0000 | 0.01 | 0.83 | 1.23 | [16] | LC |
rs1926203 | ACTA2 | T/G | 0.67(1466) | 0.67(36273) | 0.0000 | 0.99 | 0.90 | 1.08 | [16] | LC |
rs13361707 | PRKAA1 | T/C | 0.57(4294) | 0.48(5882) | 0.0000 | 1.42 | 1.24 | 1.62 | [20] | GA |
rs2808630 | CRPP1/CRP | C/T | 0.40(96) | 0.41(124) | 0.0000 | 1.04 | 0.74 | 1.36 | [16] | LC |
rs753955 | MIPEP/TNFRSF | C/T | 0.33(2331) | 0.28(3065) | 0.000 | 1.24 | 1.14 | 1.35 | [14] | LC |