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. 2017 May 18;12(5):e0177428. doi: 10.1371/journal.pone.0177428

Table 1. General tumour growth parameters for the different groups.

The average allocation time is given in days after injection required to achieve a tumour volume of about 10 mm3; the number of animals per group (n) and take rates are included for completeness. The differences between the scheduled (18) and actual number of animals per group arose from failed injections, i.e. by accidental ear piercing, premature dead after injection or problems with the cell suspension in the case of the FaDu PBS group.

Cell Number FaDu LN229
n Take rate Allocation rate Allocation time
/ d (± sem)
n Take rate Allocation rate Allocation time
/ d (± sem)
PBS
1*106 10 0.70 0.57 18.8 ± 2.8
1*105 19 0.84 0.69 106.2 ± 9.7
9.7 mg/ml Matrigel
1*106 16 1.0 0.69 7.4 ± 1.5
1*105 16 1.0 0.69 13.3 ± 1.7 19 0.95 0.50 23.6 ± 2.0
1*104 16 0.81 0.62 19.4 ± 2.0 19 0.89 0.75 28.5 ± 2.7
1*103 17 0.82 0.36 26.0 ± 3.0 13§ 0.92 0.36 45.8 ± 3.9
1*102 18 0.39 0.0 ---
4.85 mg/ml Matrigel (MG:PBS 1:1)
1*106 15 0.93 0.21 13.7 ± 4.6
1*105 16 0.94 0.53 18.9 ± 1.1
1*104 16 0.94 0.53 24.9 ± 2.3
1*103 16 0.56 0.44 27.8 ± 1.7

§ During injection of the 2nd cohort of LN229 premature gelatinisation of MG causes a stop of injection in that particular group; the remaining animals of that group were allotted to the other groups.