Table 2. Patient data.
| Test set | Reference set | |||||||
|---|---|---|---|---|---|---|---|---|
| OSCC patients (BioPlex) | Age-matched control patients (Bioplex) | OSCC patients (mass spectrometry) | Age-matched control patients (MC—mass spectrometry) | Young healthy control patients (HC—mass spectrometry) |
OSCC patients (ELISA) | Age-matched control patients (MC-ELISA) | Young healthy control patients (YC-ELISA) |
|
| Total number | 22 | 10 | 13 | 15 | 8 | 26 | 12 | 7 |
| Age | 61.9±7.8 (49–77) | 63.5±6.7 (53–73) | 60.8±7.5 (52–77) | 64.9±10.4 (52–87) | 24.3±1.9 (22–28) | 58.2±9.7 (44–77) | 59.3± 5.6 (50–68) | 24.4± 1.3 (22–26) |
| Sex M/F | 18/4 | 9/1 | 11/2 | 11/4 | 3/5 | 20/6 | 3/9 | 4/3 |
| Socioeconomical status | ||||||||
| · low/middle/ high | 6/14/0 | 2/6/2 | 4/7/0 | 0/10/5 | 0/0/8 | 7/17/1 | 2/8/0 | 0/0/5 |
| Smoking habit | ||||||||
| · Never smoker | 5% | 40% | 7.7% | 79% | 62.5% | 4% | 41% | 43% |
| · Ex-smoker | 22% | 10% | 23% | 21% | 12.5% | 23% | 25% | 14% |
| · Current smoker | 68% | 50% | 61.6% | - | 12.5% | 69% | 17% | 14% |
| · No response | 5% | - | 7.7% | - | 12.5% | 4% | 17% | 29% |
| Alcohol consumption | ||||||||
| · Never/rarely | 2/3 | 2/1 | 1/0 | 4/3 | 0/3 | 4/6 | 4/2 | 0/3 |
| · Monthly/ weekly | 4/4 | 4/3 | 4/1 | 3/3 | 3/1 | 3/8 | 0/4 | 2/0 |
| · Daily | 8 | - | 6 | 0 | 0 | 4 | 0 | 0 |
| · Intake (mL/day) | beer 285 mL/day/person |
beer 171 mL/day/person |
beer 426 mL/day/person |
beer 30 mL/day/person |
beer 33 mL/day/person |
beer 162 mL/day/person |
beer 171 mL/day/person |
beer 0 mL/day/person |
| wine / champagne 94 mL/day/person |
wine / champagne 34 mL/day/person |
wine / champagne 130 mL/day/person | wine / champagne 11 mL/day/person |
wine / champagne 11 mL/day/person | wine / champagne 84 mL/day/person |
wine / champagne 31 mL/day/person |
wine / champagne 23 mL/day/person |
|
| spirits 25 mL/day/person |
spirits 0 mL/day/person |
spirits 28 mL/day/person |
spirits 9 mL/day/person |
spirits 10 mL/day/person |
spirits 24 mL/day/person |
spirits 0 mL/day/person |
spirits 0 mL/day/person |
|
| Periodontal assessment | ||||||||
| · Gingival index | 0.7 | 0.3 | 0.9 | 0.5 | 0.5 | 0.7 | 0.2 | 0.3 |
| · Plaque index | 1.4 | 0.4 | 1.6 | 0.3 | 0.2 | 1.3 | 0.6 | 0.3 |
| Cariological assessment | ||||||||
| · DMFT | 23.1 | 19.7 | 23 | 18.9 | 7.5 | 26.9 | 26 | 8.3 |
| · DMFS | 99.8 | 81.6 | 67.5 | 79.9 | 17.5 | 121.6 | 117.8 | 18.0 |
| Comorbidities | ||||||||
| ·Hypertonia+Cardiovascular disease | 1 | 2 | 1 | 1 | - | 6 | 2 | - |
| · Hypertonia | 4 | 2 | 4 | 4 | - | 8 | 3 | - |
| · Cardiovascular disease | 6 | 0 | 4 | 0 | - | 2 | - | |