Table 1. Clinical and pathological features of all the patients.

IID	Sex	Age/AO	URBC (104/ml)	Pro (g/24h)	Scr (mg/dl)	HT	EE	RB			FH
								LM	EM	α3,α5
1	M	25/24.5	138	6.19	2.32	SH	n.a.	FSGS	L	A,A	P
2	M	15/14	56–225	14.25	0.64	Nor	Nor	FSGS	L	M,M	P
3	M	9/3	1800	1.14	0.60	SH	n.a.	FSGS	L	A,A	P
4	M	25/25	140	5.78	2.64	SH	CC	FSGS	L	M,A	P
5	M	18/18	120	5.46	1.99	SH	n.a.	FSGS	L	M,A	P, C
6	M	21/21	46	4.80	2.43	SH	Nor	FSGS	L	A,A	P
7	M	23/23	46	1.62–1.39	1.07	Nor	Nor	FSGS	L	Nor,M	P
8	M	13/13	110	1.12	0.62	SH	Nor	FSGS	L	M,M	P, C
9	M	15/2	120	6.88	0.89	SH	Nor	FSGS	L	A,A	P
10	M	12/12	15	1.75	0.34	Nor	Nor	FSGS	L	A,A	N
11	F	13/5	640–1200	0.43–1.01	0.54	Nor	Nor	FSGS	L	M,M	P
12	M	23/23	85–226	2.32	0.95	Nor	Nor	FSGS	L	Nor,A	N
13	M	14/11	260	1.79	0.69	Nor	Nor	FSGS	L	A,A	P
14	M	37/26	80	1.13	1.25	SH	n.a	FSGS	L	Nor,M	P
15	M	14/14	490	11.16	2.13	SH	Iso	FSGS	L	A,A	P
16	M	36/32	16	0.71	1.30	Nor	Nor	FSGS	L	A,A	N
17	M	22/16	42	1.22	0.79	n.a.	Nor	FSGS	L	M,M	N
18	M	17/10	77	4.36	1.22	SH	Nor	FSGS	L	A,A	P
19	F	23/2	100	1.22	0.62	n.a.	n.a.	FSGS	L	Nor,Nor	P
20	M	14/10	300	1.71	0.84	SH	CI	FSGS	L	A,A	N

IID, individual ID; AO, age at onset; URBC, urine red blood cell (10⁴/ml); Pro, proteinuria(g/24h); nephritic proteinuria (defined as 24-h urine protein excretion >3.5g); Scr, serum creatinine(mg/dL); normal renal function (defined as SCr<1.24mg/dl); RB, renal biopsy; LM, light microscope; EM, electron microscope; α3,α5, α3,α5 chains in GBM; A, absence; M, mosaic; HT, hearing test; L, lamellation; SH, sensorineural hearing loss; Nor, normal; n.a., not available; EE, eye examination; CC, conjunctival congestion; Iso, Isoametropic; CI, corneal injury; FH, family history; P, positive; N, negative; C: Consanguineous.