. Author manuscript; available in PMC: 2017 May 18.

Published in final edited form as: Am J Med Genet A. 2014 Nov 25;167A(2):379–384. doi: 10.1002/ajmg.a.36850

Table 2.

Fraction of FXS cohort With TC, HDL, and LDL Below the 10^th Centile.

	TC			HDL			LDL
Group	# (%<10^%ile)	CI	P	# (% <10^%ile)	CI	p	# (% 10^%ile)	CI	P
Males 4–19	16/56 (28.6)	16.7–40.4	<0.0001	17/45 (37.8)	23.6–51.9	<0.0001	5/30 (16.7)^*	3.3–30	0.22
Males 20+	7/32 (21.9)	7.5–36.2	0.025	9/22 (40.9)	20.4–61.4	<0.0001	7/21 (33.3)	13.2–53.5	0.0004
All Males	23/88 (26.1)	17–35.3	<0.0001	26/67 (38.8)	27.1–50.5	<0.0001	12/51 (23.5)	11.9–35.2	0.001
Females	5/15 (33.3)	11.8–61.6	0.03	1/9 (11.1)	0.3–48.3	1.0	2/6 (33.3)	4.3–77.7	0.23

The normal LDL values for children under 12 in the general population were not available so only LDL data from the FXS cohort of patients 12 and over was used for the analysis.