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. 2017 May 18;12(5):e0177728. doi: 10.1371/journal.pone.0177728

Table 1. Dilution ranges and breakpoints for antimicrobial susceptibility testing.

Antimicrobial Range Breakpoint*
Ampicillin 0.5–16 ≥16
Chloramphenicol 2–32 ≥32
Daptomycin 0.125–4 ≥8
Erythromycin 0.25–8 ≥8
Flavomycin 1–32 ≥32
Gentamicin 32–1024 ≥512
Kanamycin 128–1024 ≥1024
Lincomycin 1–32 ≥8
Linezolid 0.5–8 ≥8
Penicillin 0.5–16 ≥16
Streptomycin 256–1024 ≥1024
Teicoplanin 0.125–4 2
Tetracycline 2–16 ≥16
Tigecycline 0.016–0.5 ≥0.5
Vancomycin 0.25–32 ≥32
Virginiamycin 1–32 >8

* CLSI breakpoints were adopted for ampicillin, daptomycin, erythromycin, linezolid, penicillin and vancomycin. NARMS breakpoints were used for chloramphenicol, flavomycin, gentamicin, kanamycin, lincomycin, streptomycin, tetracycline, tigecycline with EUCAST breakpoints used for teicoplanin and virginiamycin.