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. 2017 May 11;10:1125–1134. doi: 10.2147/JPR.S131104

Figure 2.

Figure 2

Change in PWTs on days 1, 4, 7, and 10 after CCI and sham treatment.

Notes: PWTs were assessed by plantar test. (A) Mechanical withdrawal thresholds in plantar surface of hind paw decrease over time, and hyperalgesia develops ipsilaterally after sciatic nerve injury. (B) Mechanical withdrawal latency also decreased over time. All data points represent the mean ± SD. Two-way ANOVA was used to assess statistical differences; *P<0.05. CCI rats responded with significantly shorter latencies to mechanical stimulation of the plantar area of the ipsilateral hind paw than did sham-treated rats. Sham-treated (n=10); CCI (n=20).

Abbreviations: ANOVA, analysis of variance; CCI, chronic constriction injury; PWTs, paw withdrawal thresholds; SD, standard deviation.