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. Author manuscript; available in PMC: 2017 May 18.
Published in final edited form as: Int Educ Res J. 2016 Dec;2(12):91–97.

Figure 7. Treatment with rapamycin causes G1 phase arrest in porcine cells but not in mouse-derived cells.

Figure 7

In our cell cycle assay, BrdU incorporation was used to resolve cell cycle phases. (A) In epithelial cells treated with rapamycin the cell population was shifted more towards a G0/G1 phase by a significant amount. The rapamycin treated cells also had lower levels of BrdU incorporation indicating a G1 phase arrest. The population of cells in S-phase were found to be significantly reduced after rapamycin treatment. For mice epithelial (B) and endothelial (C) cells, no significant variation in cell cycle was seen in rapamycin-treated cells compared to control. * = p<0.05 compared to corresponding controls.