Table 4. Factors in dark condition associated with light-to-dark changes in I-area by univariate and multiple regression between the left eyes of CPACG patients (including 31 PACG eyes and 26 PAC/PACS eyes) and normal control eyes.
| Invariable | Multivariable | ||||
|---|---|---|---|---|---|
| β | P | Direction | β | P | |
| Sex | -0.023 | 0.559 | |||
| Age (years) | -0.002 | 0.439 | |||
| IOP (mmHg) | 0.001 | 0.727 | |||
| AL (mm) | 0.037 | 0.069 | |||
| Extent of PAS (clock-hours) | -0.007 | 0.172 | |||
| ACA (mm2) | 0.026 | <0.001 | 0.013 | 0.098 | |
| LV (mm) | -0.292 | <0.001 | 0.116 | 0.305 | |
| LT (mm) | -0.132 | 0.004 | -0.055 | 0.301 | |
| IC (mm) | -1.519 | <0.001 | Eyes with smaller IC in the dark condition exhibited greater light-to-dark change in I-area | -1.244 | <0.001 |
| IT500μm (mm) | 1.222 | <0.001 | 0.209 | 0.501 | |
| PD (mm) | 0.104 | <0.001 | 0.012 | 0.599 | |
| Diagnostic groups 1 | -0.087 | 0.041 | 0.087 | 0.589 | |
| Diagnostic groups 2 | -0.212 | <0.001 | Compared to control eyes, PACG eyes exhibited smaller light-to-dark change in I-area | -0.115 | 0.042 |
Diagnostic groups 1: PAC/PACS eyes vs normal control eyes
Diagnostic groups 2: PACG eyes vs normal control eyes
I-area: Iris cross-sectional area
IOP: Intraocular pressure
AL: Axial length
PAS: Peripheral anterior synechiae
ACA: Anterior chamber cross-sectional area
LV: Lens vault
LT: Lens thickness
IC: Iris curvature
IT500μm: Iris thickness 500μm from the iris root
PD: Pupil diameter