Skip to main content

View full-text article in PMC

. 2017 May 18;12(5):e0177903. doi: 10.1371/journal.pone.0177903

Table 3. Associations of MRI features between triple-negative and ER-positive breast cancers.

			Univariate		Multivariate
Variable	ER-Positive (n = 149)	Triple-Negative (n = 72)	OR (95% CI)	p value	OR (95% CI)	p value
DWI rim
negative	86 (57.72)	42 (58.33)	Reference
positive	63 (42.28)	30 (41.67)	0.98 (0.55, 1.72)	0.931^a
ADC mean (10^-3mm²/s)			1.002 (1.001, 1.003)	<0.001^a^,^b	1.0008 (0.99, 1.007)	0.816^a
mean±SD	0.962 ± 0.366	1.129 ± 0.181
median (IQR)	1.054 (0.678, 1.187)	1.119 (0.997, 1.231)
ADC mode (10^-3mm²/s)			1.0013 (1.0005, 1.0022)	0.002^a^,^b	0.9997 (0.998, 1.001)	0.686^a
mean±SD	0.813 ± 0.386	0.976 ± 0.286
median (IQR)	0.863 (0.547, 1.050)	0.979 (0.800, 1.150)
ADC 25 percentile (10^-3mm²/s)			1.002 (1.001, 1.004)	<0.001^a^,^b	0.999 (0.995, 1.003)	0.814^a
mean±SD	0.753 ± 0.306	0.914 ± 0.187
median (IQR)	0.823 (0.532, 0.957)	0.926 (0.767, 1.014)
ADC 50 percentile (10^-3mm²/s)			1.002 (1.001, 1.003)	<0.001^a^,^b	1.002 (0.994, 1.01)	0.616^a
mean±SD	0.937 ± 0.361	1.101 ± 0.190
median (IQR)	1.032 (0.676, 1.162)	1.081 (0.981, 1.198)
ADC 75 percentile (10^-3mm²/s)			1.0011 (1.0003, 1.0019)	0.007^a
mean±SD	1.156 ± 0.448	1.310 ± 0.212
median (IQR)	1.246 (0.827, 1.440)	1.293 (1.179, 1.438)
ADC skewness			1.86 (1.18, 3)	0.008^a
mean±SD	0.29 ± 0.57	0.53 ± 0.73
median (IQR)	0.25 (-0.03, 0.64)	0.48 (0.11, 0.97)
ADC kurtosis			1.67 (1.38, 2.06)	<0.001^a^,^b	1.71 (1.37, 2.19)	<0.001^a^,^b
mean±SD	0.39 ± 1.46	1.79 ± 1.92
median (IQR)	-0.004 (-0.46, 0.82)	1.24 (0.29, 3.01)

^aThe significance threshold for difference was set at a P value less than 0.00625 (0.05/8) for multiple comparison correction.

^bStatistically significant.