Fig 5. Effects of a WBP1 antisense oligonucleotide GapmeR on WBP1 expression and development of the embryo to the blastocyst stage.

A. Transcript abundance for WBP1 expression in 9–16 cell preimplantation embryos at 72–76 hpi. Data are least-squares means ± SEM of fold-change values relative to the vehicle treatment. B and C. Development at Day 7 (B), and Day 8 (C) of development. Data are least-squares means ± SEM of percent of putative zygotes that reached the blastocyst stage.