Table 3.
Disorders | Total sample | Sex-limitation | ||||
---|---|---|---|---|---|---|
| ||||||
Female | Male | |||||
| ||||||
A | E | A | E | A | E | |
Broad migraine^ | 0.56 (0.53–0.60) | 0.44 (0.40–0.47) | 0.60 (0.55–0.64) | 0.40 (0.36–0.45) | 0.49 (0.41–0.56) | 0.51 (0.44–0.59) |
Broad depression^ | 0.42 (0.37–0.47) | 0.58 (0.53–0.63) | 0.44 (0.38–0.50) | 0.56 (0.50–0.62) | 0.40 (0.31–0.48) | 0.60 (0.52–0.69) |
Bivariate variance | 0.055 (0.036–0.078) | 1.5×10−3 (3.4×10−6–7.1×10−3) | 0.047 (0.026–0.074) | 4.1×10−6 (4.1×10−6–4.2×10−6) | 0.058 (0.024–0.11) | 7.3×10−3 (2.1×10−5–0.028) |
Correlation | 0.36 (0.29–0.43) | 0.050 (−0.011–0.11) | 0.32 (0.25–0.41) | 2.7×10−3 (−0.075–0.080) | 0.38 (0.25–0.52) | 0.11 (5.4×10−3–0.21) |
A: additive genetic factors; E: unique environmental factors.
Three phenotype categories for broad migraine: non-migraine, self-report/ID migraine and IHS MO/MA; three phenotype categories for broad depression: non-depressed, MiDD and MDD.