Table 1.
Baseline Patient Characteristics Stratified by Receipt of HCC Surveillance
| Variable | All Patients (n=1137) | Surveillance (n=393) | No Surveillance (n=744) | p-value |
|---|---|---|---|---|
| Age | 60 [54, 70] | 59 [54, 65] | 61 [54, 72] | 0.004 |
| Gender (% male) | 583 (51.3) | 204 (51.9) | 379 (50.9) | 0.80 |
| Race/ethnicity* | 0.25 | |||
| White | 865 (76.1) | 299 (76.1) | 566 (76.1) | |
| Black | 60 (5.3) | 23 (5.9) | 37 (5.0) | |
| Hispanic | 56 (4.8) | 17 (4.3) | 39 (5.2) | |
| Asian | 89 (7.8) | 38 (9.7) | 51 (6.9) | |
| Etiology of Liver Disease* | < 0.001 | |||
| Hepatitis C | 329 (28.9) | 157 (39.9) | 172 (23.1) | |
| Hepatitis B | 36 (3.2%) | 25 (6.4) | 11 (14.8) | |
| Alcohol-related | 184 (16.2) | 66 (16.8) | 118 (15.9) | |
| NASH | 326 (28.7) | 79 (20.1) | 247 (33.2) | |
| Other | 262 (23.0) | 66 (16.8) | 196 (26.3) | |
| Child Pugh Class (% Child A) | 1013 (89.1) | 332 (84.5) | 681 (91.5) | <0.001 |
| Presence of ascites | 873 (76.8) | 282 (71.8) | 591 (79.4) | 0.004 |
| Presence of hepatic encephalopathy | 1061 (93.3) | 359 (91.3) | 702 (94.4) | 0.06 |
| Platelet count (*103/μL) | 175 [113,240] | 141 [95, 202] | 203 [130, 257] | <0.001 |
| AST (U/L) | 35 [25, 57] | 40 [28, 68] | 31 [23, 50] | <0.001 |
| Albumin (g/dL) | 4.2 [3.8, 4.4] | 4.2 [3.8, 4.4] | 4.2 [3.9, 4.4] | 0.35 |
| Bilirubin (mg/dL) | 0.6 [0.4, 1.0] | 0.6 [0.4, 1.1] | 0.5 [0.4, 0.8] | <0.001 |
| INR | 1.1 [1.0, 1.3] | 1.1 [1.0, 1.3] | 1.1 [1.0, 1.4] | 0.48 |
| Charlson comorbidity index | 1 [0, 3] | 1 [0, 3] | 1 [0, 3] | 0.18 |
| Number primary care visits in year prior to index visit | 7 [4, 11] | 7 [3, 12] | 7 [4, 11] | 0.99 |
| Gastroenterology/Hepatology visits in year prior to index visit | 0 [0, 1] | 0 [0, 2] | 0 [0, 1] | <0.001 |
| Gastroenterology/Hepatology care in year prior to index visit | 422 (37.1) | 190 (48.4) | 232 (31.2) | < 0.001 |
| Neighborhood-level Income quartile | 3 [2, 3] | 3 [1, 3] | 3 [2, 4] | 0.80 |
| Neighborhood-level Education quartile | 2 [1, 4] | 2 [1, 3] | 3 [2, 4] | 0.14 |
| Distance to nearest clinic (miles) | 4 [2, 7] | 4 [2, 7] | 4 [2, 7] | 0.90 |
Note: All values are reported as median (interquartile range) or n (%) unless otherwise specified.
*
Data regarding race/ethnicity were missing in 60 patients
AST – aspartate aminotransferase; HCC – hepatocellular carcinoma; INR – international normalized ratio; NASH – nonalcoholic steatohepatitis