The higher temporal stability of sub millimeter voxels shown for one representative subject in Fig. 2 is consistent across participants of the study. For both, BOLD and VASO time series, tSNR values are higher for 3D-segmented-EPI compared to 2D-EPI. Note that BOLD and VASO figures are acquired simultaneously, while 3D-segmented-EPI and 2D-EPI figures are acquired in separate experiments 12 minutes apart. Hence, due to participants head motion between experiment, the slice position can be minimally different. Since the slice positioning and slice tilting was adjusted to be perpendicular to the participants individual M1 cortex, the FOV contains different brain regions for different participants.