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. 2017 May 18;7:2099. doi: 10.1038/s41598-017-02296-w

Figure 2.

Figure 2

PSAT1 expression and clinical relevance in the TMA and Affymetrix datasets. Breast carcinoma IHC stained tissues either displayed high or low PSAT1 protein levels. Two representative specimen having either high or low PSAT1 are presented (panel A). Kaplan-Meier analysis showed that high expression of PSAT1 protein was significantly associated to shorter TTP when compared to tumors with low PSAT1 levels (panel B). PSAT1 mRNA levels were assessed by Affymetrix GeneChip. Statistical analysis not only showed PSAT1 mRNA expression was enrihed in poor outcome patients (t test P = 0.014; panel C), but Kaplan Meier analysis showed that, also in this set, PSAT1 expression was significantly associated to shorter TTP (panel D).