Table 3.

Univariate and multivariate analysis of clinicopathological factors for overall survival.

Clinicopathological	Subset	Univariate analysis			Multivariate analysis
		HR	95% CI	p value	HR	95% CI	p value
Age (years)	<35 vs. >=35	1.116	0.628–2.121	0.589
Histology	Squamous vs. Adenocarcinoma	1.128	0.477–2.691	0.748
HPV	HPV16, HPV18 vs. Others	1.498	0.774–2.987	0.231
FIGO stage	Ib~IIa vs. IIb~IIIa	3.618	1.935–6.984	<0.0001	2.318	1.157–4.646	0.018
Histological differentiation	Well vs. moderate, poor	0.725	0.400–1.382	0.472
Lymph node metastasis	Positive vs. negative	4.253	2.424–8.308	<0.0001	2.236	1.144–4.926	0.005
Recurrence	Yes vs. No	1.708	0.802–3.813	0.139
Tumor maximum diameter (cm)	<4 vs. >=4	1.374	0.624–2.491	0.539
CKAP2 expression	High vs. Low	4.686	2.175–9.882	<0.0001	2.383	1.234–6.481	0.013