Table 4.
Congenital malaria detection in cord blood samples according to LM, RDT and ELISA compared to qPCR.
| Diagnostic tools | Total | qPCR | Sensitivity (95% CI) | Specificity (95% CI) | |
|---|---|---|---|---|---|
| Positive (n = 16) | Negative (n = 384) | ||||
| RDT | |||||
| Positive | 3 | 2 | 1 | 12.5 (2.2–39.6) | 99.7 (98.3–100) |
| Negative | 397 | 14 | 383 | ||
| LM | |||||
| Positive | 0 | 0 | 0 | 0 (0–24.1) | 100 (98.8–100) |
| Negative | 400 | 16 | 384 | ||
| ELISA | |||||
| Positive | 6 | 2 | 4 | — | — |
| Negative | 394 | 14 | 380 | ||
qPCR, quantitative real-time Polymerase Chain Reaction; LM, Light Microscopy; RDT, Rapid Diagnostic Test; ELISA, Enzyme-Linked ImmunoSorbent Assay; CI, Confidence Interval.