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. 2017 May 19;11:267. doi: 10.3389/fnhum.2017.00267

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Copyright © 2017 Chen, Chen, Ding, Zhang, Yang, Lv, Guo and Han.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The atrophy and degree-centrality maps in subjects. In the atrophy map of SD (A), the degree centrality value of the left anterior hippocampus (aHIP) (D) was significantly lower in SD patients (B) relative to healthy controls (C) (AlphaSim corrected p < 0.05); (E) correlation of the left aHIP-seeded degree-centrality values with semantic composite scores in SD. [the geometric figures (circle, square, and triangle) and numbers circling the dots show the three patients with multiple observations and their observation times, respectively].