Table 2.
Correlation coefficients between the integrity index of functional or structural connectivity of the left aHIP and the index of behavioral deficits in SD patients.
| Connectivity type | Region connecting with the left aHIP | Connectivity integrity index | Correlation with semantic performance |
Correlation with non-semantic task performance |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Raw correlation | Correlation with the following variable as covariate |
Number calculation | Episodic memory | |||||||
| Total gray-matter volume | Structural signal intensity of the seed | Functional signal intensity of the seed | Covariation of multiple observations | All the four variables | ||||||
| FC | Left TP/INS | FC intensity | 0.75∗∗∗ | 0.70∗∗∗ | 0.64∗∗ | 0.75∗∗∗ | 0.77∗∗∗ | 0.64∗∗ | 0.18 | 0.33 |
| Left MTG | FC intensity | 0.67∗∗∗ | 0.65∗∗ | 0.45∗ | 0.67∗∗ | 0.69∗∗∗ | 0.51∗ | 0.01 | 0.23 | |
| SC | Left TP/INS | FA value | -0.20 | -0.34 | -0.29 | -0.21 | -0.16 | -0.39 | -0.24 | -0.30 |
| LDH value | -0.52∗ | -0.48∗ | -0.44# | -0.51∗ | -0.51∗ | -0.42# | 0.20 | -0.11 | ||
#p < 0.10, ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. aHIP, anterior hippocampus; FA, fractional anisotropy; FC, functional connectivity; INS, insula; LDH, local diffusion homogeneity; MTG, middle temporal gyrus; SC, structural connectivity; TP, temporal pole.