Table 1.
Main clinical and microbiological characteristics of the 14 selected S. aureus strains.
| Strain | Acquisition | Clinical diagnosis | Persistent bacteremia | Septic complication | Severe sepsis | In-hospital mortality | CC | MSSA/MRSA | Functional Agr | Agr type |
|---|---|---|---|---|---|---|---|---|---|---|
| SA80001 | CA | Native mitral valve endocarditis | >3 days | Yes (CNS) | No | No | 30 | MSSA | Yes | 3 |
| SA107 | HCA | Catheter-related bacteremia | No | Yes (lung) | No | No | 30 | MSSA | No | 3 |
| SA123 | HCA | Native mitral valve endocarditis | No | Yes (thrombophlebitis) | Yes | No | 45 | MSSA | Yes | 1 |
| SA520 | HCA | Native mitral valve endocarditis | >3 days | – | No | No | 45 | MSSA | Yes | 1 |
| SA170015 | HCA | Prosthetic mitral valve endocarditis | No | No | No | No | 45 | MRSA | Yes | 1 |
| SA103 | HCA | Native mitral valve endocarditis | No | Yes (thrombophlebitis) | No | No | 5 | MSSA | Yes | 2 |
| SA80004 | HCA | Native mitral valve endocarditis | No | No | No | No | 5 | MSSA | No | 2 |
| SA170006 | HCA | Native aortic valve endocarditis | >3 days | Yes (liver, spleen, kidney) | No | No | 5 | MRSA | No | 2 |
| SA180009 | HCA | Prosthetic aortic valve endocartidis | >7 days | Yes (perivalvular abscess) | No | Yes | 5 | MRSA | Yes | 2 |
| SA10009 | CA | Native mitral valve endocarditis | No | No | No | No | 15 | MSSA | Yes | 2 |
| SA10014 | CA | Native aortic valve endocarditis | >7 days | Yes (spleen, kidney) | Yes | Yes | 15 | MSSA | Yes | 2 |
| SA180015 | CA | Prosthetic aortic & mitral valve endocarditis | No | Yes (perivalvular abscess) | No | No | 8 | MSSA | No | 1 |
| SA190006 | CA | Native aortic valve endocarditis | No | No | No | Yes* | 8 | MSSA | Yes | 1 |
| SA70002 | HCA | Tricuspid endocarditis | >7 days | Yes (spondylodiscitis) | No | No | 8 | MRSA | No | 1 |
*
Klebsiella pneumoniae pulmonary infection. CC, clonal complex; MSSA, methicillin susceptible S. aureus; MRSA, methicillin resistant S. aureus; Agr, Accesory global regulator; CA, Community-associated; HCA, Healthcare-associated; CNS, central nervous system.