Table 3.
Virulence genes variants especifically detected in CC15 strains.
| Total | Non-synonymous | Synonymous | References | |
|---|---|---|---|---|
| VIRULENCE REGULATORS | ||||
| AgrB* | 1 | 889G>A | DQ157967 | |
| AgrD* | 0 | – | – | DQ157967 |
| AgrC* | 11 | – | 1739T>C; 1743A>G; 1754G>A; 1763C>T; 1769C>T; 1775A>G; 1787A>T; 1790T>C; 1793T>C; 1796T>C; 2030A>G | DQ157967 |
| AgrA* | 5 | 2818A>G (136K>R) | 2801C>T; 2810G>A; 2813G>A; 2816T>A | DQ157967 |
| Rot | 1 | – | 126T>Aa | CP012692 |
| SarA | 0 | – | – | CP017094 |
| CodY | 0 | – | – | CP012409 |
| SarR | 0 | – | – | CP012409 |
| SaeR | 0 | – | – | CP016861 |
| SaeS | 0 | – | – | CP016856 |
| SrrA | 0 | – | – | CP012976 |
| SigB | 0 | – | – | CP015645 |
| HEMOLYSINS | ||||
| Hla | 1 | 319C>T (107P>S)a | – | LN626917 |
| Hld | 0 | – | – | DQ157967 |
| HlgB | 0 | – | – | CP012692 |
| HlgC | 1 | – | 925 G>A | CP012692 |
| HlgA | 0 | – | – | CP012692 |
| Psma1 | 0 | – | – | CP014444 |
| Psma2 | 0 | – | – | CP014444 |
| Psma3 | 0 | – | – | CP014444 |
| Psma4 | 0 | – | – | CP014444 |
| Psmb1 | 0 | – | – | CP014444 |
| Psmb2 | 0 | – | – | CP014444 |
| LEUCOCIDINS | ||||
| LukE | 3 | 734G>C (245G>A)a | 9T>C; 672 G>A | CP012970 |
| LukD | 10 | – | 93 A>G; 189 G>T; 201 T>G; 219 C>T; 234 A>G; 246C>T; 249 A>T; 261A>T; 801 C>T; 921 C>T | CP012970 |
| PROTEASES | ||||
| Aur | 3 | – | 1187 C/A>G; 1208 A/T>C; 1322A>T | CP010402 |
| SplA | 9 | 10G>A (4G>S); 64A>G (22N>D); 70C>T (24P>S); 257C>T (86S>L); 527A>G (176D>G); 554G>A (185G>E) | 231T>C; 438T>C; 618T>C | CP012978 |
| SplB | 1 | – | 495 T>C | CP012978 |
| SplE | 1 | 551C>G (184A>G) | – | CP012978 |
| IMMUNE EVASION GENES | ||||
| Scn | 0 | – | – | CP012120 |
| Chp | 2 | 315T>A (46M>L) | 256C>T | CP012120 |
*
Results from the comparison of CC15 only with CC45 (type II Agr).
a
Only detected in one of the two CC15 strains.