Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Mar 27;292(20):8331–8341. doi: 10.1074/jbc.M116.772327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

Figure 2. — DDX41 controls the expression of p21 independent of caspase-2. A, Western blot analyses for the presence of the indicated proteins in immunoprecipitates of the BrU-labeled 3′UTR-containing p21 mRNA. Before immunoprecipitation (IP), the p21 mRNA was incubated for 2 h with cytoplasmic extracts of HCT116 wild-type cells that were transfected with control or caspase-2 siRNA. Cytoplasmic extracts that were not subjected to RNA immunoprecipitation served as controls (Input). B and C, Western blot analyses for the status of the indicated proteins in extracts of HCT116 wild-type cells transfected with either control or caspase-2 siRNA. Samples were probed at the indicated times after γIR. The blots shown are representative results of five (A) and three (B and C) independent experiments.