Table 2. Descriptive analyses of nailfold microvascular features in exfoliation syndrome/exfoliation glaucoma (XFS/XFG), primary open-angle glaucoma (POAG), and control subjects.
| Nailfold microvascular features | XFS/XFG (n=56) | POAG (n=87) | Controls (n=75) | P-valuea for XFS/XFG vs Controls | P-valuea for POAG vs Controls | P-valuea for XFS/XFG vs POAG |
|---|---|---|---|---|---|---|
| Number of hemorrhages per 100 capillaries, n (%) | <0.0001 | <0.0001 | 0.64 | |||
| 0.0 | 22 (39.3) | 25 (28.7) | 51 (68.0) | |||
| >0.0 and <1.0 | 10 (17.9) | 28 (32.2) | 15 (20.0) | |||
| ≥1.0 | 24 (42.9) | 34 (39.1) | 9 (12.0) | |||
| Number of avascular zones ≥200 μm per 100 capillaries, n (%) | <0.0001 | <0.0001 | 0.001 | |||
| 0.0 | 11 (19.6) | 35 (40.2) | 60 (80.0) | |||
| >0.0 and <0.5 | 6 (10.7) | 17 (19.5) | 7 (9.3) | |||
| ≥0.5 | 39 (69.6) | 35 (40.2) | 8 (10.7) | |||
| Mean tortuosity score,b n (%) | <0.0001 | 0.02 | 0.0004 | |||
| <1.0 | 14 (25.0) | 39 (44.8) | 50 (66.7) | |||
| ≥1.0 and <1.5 | 12 (21.4) | 29 (33.3) | 14 (18.7) | |||
| ≥1.5 | 30 (53.6) | 19 (21.8) | 11 (14.7) |
a
Mantel–Haenszel χ2 test.
b
Tortuosity scores assigned at the 1-min and 2-min time points on both fingers assessed. Mean tortuosity score is the average of four tortuosity ratings per patient.