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. 2017 May 19;12:13. doi: 10.1186/s13020-017-0134-0

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — JTD alleviates renal histopathology and the ultrastructural pathology of the kidney. a Electron microscopy (EM) analysis of the renal cortex, representative images of glomerular basement membrane thickening and mesangial matrix expansion (scale bar 2 μm; original magnification electron microscopy ×8000; b hematoxylin and eosin (HE) staining of the kidney (original magnification ×400); c periodic schiff-methenamine (PASM) staining of the kidney (original magnification ×400); d JTD lowers the ratio of the mesangial matrix area to the total glomerular area (M/G) via PASM staining. Data are expressed as the mean ± S.D.; N = 5; *P < 0.05; **P < 0.01; and ***P < 0.001 compared to the model group