Table 1.
Multiple cause of death analysis, comparing certificates of AIDS deaths and non-AIDS/HIV deaths: crude proportions of deaths and age-standardized proportion ratio (ASPR)§, with corresponding 95% confidence intervals (CI), by any mentioned cause of death
| Cause of death mentioned in the death certificate | Crude proportion (%) | ASPR | 95% CI | ||
|---|---|---|---|---|---|
| ICD-10 code | Description | AIDS deaths (Total no. 2,515) |
Non-AIDS/HIV deaths (Total no. 123,224) |
||
| A00-B99 | Infectious and parasitic diseases (excluding B20-B24) a | 51.7 | 7.4 | 7.0 | (6.7 – 7.3) |
| B58 | Toxoplasmosis | 3.3 | <0.1 | 4167.4 | (583.4 – 29,769.1) |
| B45 | Criptococcosis | 1.8 | <0.1 | 480.4 | (192.1 – 1,201.2) |
| A31 | Infection due to other mycobacteria | 2.1 | <0.1 | 330.3 | (157.4 – 693.0) |
| B59 | Pneumocystosis | 3.1 | <0.1 | 208.1 | (129.6 – 334.2) |
| B55 | Leishmaniasis | 0.4 | <0.1 | 188.0 | (39.5 – 894.1) |
| A81 | Atypical virus infections of central nervous system | 2.7 | <0.1 | 63.6 | (44.4 – 91.1) |
| B25 | Cytomegaloviral disease | 4.8 | 0.1 | 62.9 | (48.7 – 81.4) |
| B37 | Candidiasis | 4.0 | 0.1 | 50.1 | (37.7 – 66.5) |
| A16 | Respiratory tuberculosis. not confirmed bacteriologically or histologically | 1.2 | 0.1 | 15.6 | (10.5 – 23.1) |
| B18 | Chronic viral hepatitis | 23.9 | 1.8 | 13.1 | (12.1 – 14.2) |
| A49 | Bacterial infection of unspecified site | 0.5 | 0.1 | 8.2 | (4.3 – 15.8) |
| B44 | Aspergillosis | 0.4 | 0.1 | 6.5 | (3.7 – 11.6) |
| B16 | Acute hepatitis B | 1.4 | 0.2 | 5.9 | (4.1 – 8.5) |
| A41 | Other septicemia | 12.2 | 4.7 | 2.6 | (2.4 – 2.9) |
| C00-D48 | Neoplasms a | 28.7 | 47.2 | 0.6 | (0.6 – 0.7) |
| C46 | Kaposi’s sarcoma | 2.7 | <0.1 | 298.9 | (162.4 – 550.1) |
| C83 | Diffuse non-Hodgkin’s lymphoma | 2.0 | 0.1 | 14.1 | (10.2 – 19.4) |
| C21 | Malignant neoplasm of anus and anal canal | 1.0 | 0.1 | 12.1 | (7.7 – 18.8) |
| C85 | Other and unspecified types of non-Hodgkin’s lymphoma | 8.4 | 1.3 | 6.5 | (5.7 – 7.5) |
| C81 | Hodgkin’s disease | 1.0 | 0.3 | 3.1 | (2.1 – 4.5) |
| C53 | Malignant neoplasm of cervix uterib | 3.9 | 1.1 | 2.8 | (1.7 – 4.6) |
| C22 | Malignant neoplasm of liver and intrahepatic bile ducts | 3.3 | 2.0 | 1.9 | (1.6 – 2.3) |
| C34 | Malignant neoplasm of bronchus and lung | 2.9 | 7.9 | 0.4 | (0.3 – 0.5) |
| C25 | Malignant neoplasm of pancreas | 0.4 | 2.3 | 0.2 | (0.1 – 0.4) |
| D50-D89 | Diseases of the blood. immunological disorderssa | 12.6 | 4.5 | 2.8 | (2.5 – 3.1) |
| D61 | Other aplastic anemias | 2.5 | 0.5 | 5.1 | (4.0 – 6.5) |
| D70 | Agranulocytosis | 0.6 | 0.2 | 2.7 | (1.6 – 4.6) |
| D69 | Purpura and other hemorrhagic conditions | 1.1 | 0.6 | 2.0 | (1.4 – 2.8) |
| E00-E90 | Endocrine. nutritional metabolic diseases a | 2.5 | 4.8 | 0.6 | (0.4 – 0.7) |
| E14 | Unspecified diabetes mellitus | 1.7 | 3.8 | 0.5 | (0.4 – 0.7) |
| F01-F99 | Mental and behavioral disorders a | 6.5 | 5.2 | 1.2 | (1.0 – 1.4) |
| F03 | Unspecified dementia | 1.0 | 0.1 | 13.1 | (8.3 – 20.5) |
| F11 | Mental and behavioral disorders due to use of opioids | 0.7 | 0.2 | 4.2 | (2.5 – 7.0) |
| F19 | Mental and behavioral disorders due to multiple drug use and use of other psychoactive substances | 2.7 | 0.7 | 3.4 | (2.6 – 4.4) |
| F09 | Unspecified organic or symptomatic mental disorder | 0.4 | 0.2 | 2.0 | (1.1 – 3.9) |
| F10 | Mental and behavioral disorders due to use of alcohol | 1.1 | 1.3 | 0.6 | (0.4 – 1.0) |
| F32 | Depressive episode | 0.4 | 1.0 | 0.5 | (0.3 – 0.8) |
| G00-H95 | Diseases of the nervous system and the sense organs a | 12.2 | 7.9 | 1.5 | (1.4 – 1.7) |
| G04 | Encephalitis. myelitis and encephalomyelitis | 2.3 | 0.2 | 14.3 | (10.6 – 19.1) |
| G93 | Other disorders of brain | 6.4 | 2.8 | 2.4 | (2.1 – 2.8) |
| G31 | Other degenerative diseases of nervous system. not elsewhere classified | 0.4 | 0.2 | 2.4 | (1.4 – 4.2) |
| G62 | Other polyneuropathies | 0.4 | 0.2 | 2.2 | (1.1 – 4.4) |
| I00-I99 | Diseases of the circulatory system a | 32.2 | 45.7 | 0.7 | (0.7 – 0.7) |
| I33 | Acute and subacute endocarditis | 0.4 | 0.1 | 2.8 | (1.5 – 5.4) |
| I27 | Other pulmonary heart diseases | 1.2 | 0.4 | 2.5 | (1.7 – 3.7) |
| I51 | Complications and ill-defined descriptions of heart disease | 4.1 | 5.4 | 0.7 | (0.6 – 0.9) |
| I50 | Heart failure | 2.9 | 3.9 | 0.7 | (0.6 – 0.9) |
| I61 | Intracerebral hemorrhage | 1.8 | 2.9 | 0.7 | (0.5 – 0.9) |
| I 25 | Chronic ischemic heart disease | 1.9 | 4.7 | 0.5 | (0.4 – 0.6) |
| I26 | Pulmonary embolism | 0.7 | 1.5 | 0.4 | (0.3 – 0.7) |
| I64 | Stroke. not specified as hemorrhage or infarction | 0.4 | 1.1 | 0.3 | (0.2 – 0.7) |
| I21 | Acute myocardial infarction | 2.1 | 7.5 | 0.3 | (0.2 – 0.4) |
| I 49 | Other cardiac arrhythmias | 0.4 | 1.9 | 0.3 | (0.2 – 0.5) |
| I10 | Essential (primary) hypertension | 1.1 | 4.9 | 0.3 | (0.2 – 0.4) |
| J00-J99 | Diseases of the respiratory system a | 33.0 | 22.0 | 1.5 | (1.5 – 1.6) |
| J84 | Other interstitial pulmonary diseases | 2.7 | 0.5 | 6.2 | (4.9 – 7.9) |
| J93 | Pneumothorax | 0.8 | 0.1 | 6.1 | (3.9 – 9.6) |
| J15 | Bacterial pneumonia. not elsewhere classified | 0.5 | 0.1 | 6.0 | (3.3 – 11) |
| J18 | Pneumonia. organism unspecified | 14.2 | 3.3 | 4.4 | (4.0 – 4.9) |
| J80 | Adult respiratory distress syndrome | 1.0 | 0.4 | 2.5 | (1.7 – 3.8) |
| J69 | Pneumonitis due to solids and liquids | 0.5 | 0.3 | 2.0 | (1.2 – 3.4) |
| J44 | Other chronic obstructive pulmonary disease | 1.4 | 1.2 | 1.5 | (1.1 – 2.0) |
| J96 | Respiratory failure. not elsewhere classified | 14.0 | 12.3 | 1.2 | (1.0 – 1.3) |
| J81 | Pulmonary edema | 3.4 | 4.6 | 0.7 | (0.6 – 0.9) |
| K00-K92 | Diseases of the digestive system a | 36.4 | 16.7 | 2.2 | (2.1 – 2.3) |
| K73 | Chronic hepatitis. not elsewhere classified | 2.5 | 0.2 | 11.0 | (8.2 – 14.7) |
| K52 | Other non-infective gastroenteritis and colitis | 0.8 | 0.1 | 6.4 | (4.1 – 9.8) |
| K74 | Fibrosis and cirrhosis of liver | 24.3 | 5.6 | 4.4 | (4.1 – 4.7) |
| K85 | Acute pancreatitis | 1.0 | 0.4 | 2.5 | (1.7 – 3.8) |
| K76 | Other diseases of liver | 6.5 | 3.0 | 2.2 | (1.9 – 2.6) |
| K72 | Hepatic failure. not elsewhere classified | 11.3 | 5.6 | 1.9 | (1.7 – 2.1) |
| K70 | Alcoholic liver disease | 1.0 | 1.8 | 0.6 | (0.4 – 0.9) |
| K56 | Paralytic ileus and intestinal obstruction without hernia | 0.8 | 1.4 | 0.6 | (0.4 – 0.9) |
| N00-N99 | Diseases of the genitourinary system a | 11.5 | 6.9 | 1.7 | (1.5 – 1.9) |
| N17 | Acute renal failure | 3.7 | 1.7 | 2.4 | (2.0 – 2.9) |
| N19 | Unspecified renal failure | 4.9 | 3.3 | 1.5 | (1.3 – 1.8) |
| R00-R99 | Symptoms signs and ill-defined causes (excluding R75) a | 41.2 | 33.1 | 1.2 | (1.2 – 1.3) |
| R16 | Hepatomegaly and splenomegaly. not elsewhere classified | 0.4 | 0.1 | 5.1 | (3.0 – 9.0) |
| R64 | Cachexia | 16.0 | 4.2 | 3.9 | (3.6 – 4.3) |
| R91 | Abnormal findings on diagnostic imaging of lung | 0.4 | 0.2 | 2.3 | (1.3 – 4.0) |
| R57 | Shock. not elsewhere classified | 8.6 | 10.1 | 0.8 | (0.7 – 1.0) |
| R40 | Somnolence. stupor and coma | 3.2 | 4.5 | 0.7 | (0.6 – 0.9) |
| V00-Y99 | External causes of death a | 8.0 | 17.2 | 0.4 | (0.4 – 0.5) |
| X42 | Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens] not elsewhere classified | 1.0 | 0.3 | 2.6 | (1.7 – 4.0) |
| X59 | Exposure to unspecified factor | 0.5 | 0.8 | 0.5 | (0.3 – 0.9) |
| V89 | Motor- or non motor-vehicle accident type of vehicle unspecified | 0.4 | 2.7 | 0.1 | (0.1 – 0.3) |
Deaths of people aged 35–54 years. Italy, 2006-2010
§Calculated as the age-standardized ratio between the proportion of deaths reporting a selected cause among AIDS deaths and the same proportion among non-AIDS/HIV deaths
aICD-10 chapter. The values of the proportion for the specific ICD-10 categories do not sum up to the totals by ICD-10 chapter because 1) only causes of death with a statistically significant ASPR and with at least 10 cases among AIDS deaths are shown and 2) each death certificate could report more than one cause within the same ICD-10 chapter
bOnly females