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. 2017 May 18;15:41. doi: 10.1186/s12951-017-0274-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 10 — Kinetic release profile of DOX from the HIDPPDNEs under NIR laser irradiation in vitro. The cumulative release curve of the HIDPPDNE-entrapped DOX (black curve) under NIR laser irradiation was established by measuring the concentrations of DOX in the supernatant through UV–Vis spectrometry (λ = 485 nm) after irradiated for 0, 10, 30, 60, 120, 180, 240, and 300 s. The NIR exposure was performed using an 808-nm laser with an intensity of 6 W/cm². The red curve indicates the temperature of the HIDPPDNE medium at each time point while the concentration of released DOX was detected. Values are mean ± s.d. (n = 3)